When dealing with NMO therapy, the range of treatments aimed at neuromyelitis optica spectrum disorder (NMOSD). Also known as NMOSD treatment, it targets immune‑mediated attacks on the optic nerves and spinal cord. Neuromyelitis optica spectrum disorder is the central disease, while Eculizumab, a complement‑inhibiting monoclonal antibody, represents a modern targeted option. Rituximab, which depletes CD20‑positive B cells, and Azathioprine, a classic immunosuppressant, round out the therapeutic toolbox. Together these agents show that NMO therapy encompasses both acute control and long‑term relapse prevention, and it requires early diagnosis to limit permanent damage.
First, an acute attack is usually tackled with high‑dose intravenous methylprednisolone followed by a rapid taper. If steroids fall short, plasma exchange steps in to remove pathogenic antibodies directly from the bloodstream. Once the crisis passes, the focus shifts to maintenance: B‑cell depletion (via rituximab) influences relapse rates, while complement inhibition (through eculizumab) improves outcomes for patients with anti‑AQP4 antibodies. Conventional agents like azathioprine or mycophenolate mofetil keep the immune system in check, and emerging oral therapies aim to simplify dosing. Monitoring involves regular MRI scans, antibody titres, and visual field tests to catch subclinical activity early, because “NMO therapy requires ongoing assessment” is a key tenet of effective care.
The articles below dive into specific drugs, dosing tricks, safety warnings, and real‑world comparisons. You’ll find clear breakdowns of how eculizumab stacks up against other complement inhibitors, why rituximab remains a go‑to for many clinicians, and practical tips for using steroids safely. Whether you’re a patient trying to understand your regimen or a clinician looking for a quick reference, this collection gives you actionable insights across the whole spectrum of NMO therapy.
Explore how dimethyl fumarate works for neuromyelitis optica, its clinical evidence, safety profile, dosage tips, and how it stacks up against approved NMO biologics.
